Dose-Dependent Effects of AbobotulinumtoxinA (Dysport) on Spasticity and Active Movements in Adults With Upper Limb Spasticity: Secondary Analysis of a Phase 3 Study
نویسندگان
چکیده
منابع مشابه
Effects of repeated abobotulinumtoxinA injections in upper limb spasticity
INTRODUCTION The efficacy of single injections of abobotulinumtoxinA (Dysport) is established in adults with upper limb spasticity. In this study we assessed the effects of repeated injections of abobotulinumtoxinA over 1 year. METHODS Patients (n = 258, safety population) received 500 U, 1,000 U, or 1,500 U (1,500-U dose included 500-U shoulder injections) for up to 4 or 5 treatment cycles. ...
متن کاملSystematic Literature Review of AbobotulinumtoxinA in Clinical Trials for Adult Upper Limb Spasticity
OBJECTIVE The aim of this study was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with upper limb spasticity (ULS). METHODS A systematic literature review was performed to identify randomized controlled trials and other comparative clinical studies of ABO in the treatment of adult ULS published in English between Jan...
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15 صفحه اولInvestigating muscle selection for botulinum toxin-A injections in adults with post-stroke upper limb spasticity.
BACKGROUND Limited empirical information exists regarding botulinum toxin-A injector decision-making practices for adult upper limb post-stroke spasticity. The design of most studies prevents such an assessment, as injection sites and dosage are mandated by researcher protocols. This contrasts to usual injector practices, where individualized decision-making is the standard of care. DESIGN Se...
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ژورنال
عنوان ژورنال: PM&R
سال: 2017
ISSN: 1934-1482
DOI: 10.1016/j.pmrj.2017.06.008